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With Bayesian-guided dosing software, complex calculation can be done easily, yielding more accurate results while only requiring a single blood level draw. In contrast, traditional calculation of AUC involves tedious manual calculation and two blood level draws. This increases cost, time taken and typically results in underestimation, decreasing dose efficacy.
Bayesian-guided dosing uses Bayes’ theorem with population PK parameters as Bayesian prior and a patient’s observed serum concentrations to calculate the Bayesian posterior PK parameters. Using this to derive an individualized PK profile, PrecisePK can largely reduce toxicity and improve dosing efficacy with potentially lower costs.
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Therapeutic drug monitoring projects annual savings of
Vancomycin AUC24 Bayesian software saves around
Length of hospital stay reduced up to
Incidence of nephrotoxicity can be reduced by
Yes
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Yes
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Yes
Up to 20 clones per month
Business, Technology
1 User
3 months
3 months
-
Up to 20 clones per month
Business, Technology
1 User
3 months
3 months
-
Up to 20 clones per month
Business, Technology
1 User
3 months
3 months
-
New 2020 IDSA vancomycin dosing guidelines published in March recommend monitoring the pharmacodynamic index AUC/MIC to predict the safety and efficacy of vancomycin therapy in patients ...
October 21, 2020
A 15-year-old boy with a history of leukemia, MRSA bacteremia, and acute kidney injury (AKI) needs Vancomycin stat...
October 20, 2020
PrecisePK has been in the industry for many years, formerly known as TDMS, and hence stands out as a top therapeutic drug monitoring platform due to its history. The new version is amazing visually and user-friendly too, requiring minimal training.
The unique features of this platform that I find especially helpful for patient care are flexibility in selecting neonatal, pediatric and adult models to ensure you select the best Bayesian prior for your patient population; and adjustment for special populations, including obese, critically-ill status and post-cardiac surgery.
Dr. Jennifer Le
PharmD, MAS, FIDSA, FCCP, FCSHP, BCPS-ID
Professor of Clinical Pharmacy
Director of Experiential Education in Los Angeles- Orange County Skaggs School of Pharmacy and Pharmaceutical Sciences
